The city of Colón, formerly Aspinwall, is located in the municipality of Colón and serves as the second largest city in Panama as well as a major port. The city was founded as Aspinwall in 1850 by Americans building a railroad into the isthmus but was renamed to Colón in 1890. In Wonderful Adventures of Mrs. Seacole in Many Lands  (1857), Mrs. Seacole travels by ship to distant lands through the port of Navy Bay. Navy Bay is the general term for the ports located on the island of Manzanillo, the island where the municipality of Colón is located, and Mrs. Seacole could have sailed out of the port in Colón. 

 “History of Colón, Panama.” History of Colón City, http://www.coloncity.com/history01.html.